PanaColl: A collagen-based scaffold for the delivery of antibiotics and enhancement of tissue regeneration
PanaColl is a 3D porous scaffold composed of collagen and hydroxyapatite (the two main components of native bone tissue) and can be loaded with antibiotics such as vancomycin, gentamicin and teicoplanin which are effective against bacteria including S. Aureus. The PanaColl scaffold is a dual-layered product with a dual release antibiotic profile enabling burst and sustained drug release.
miRaColl: a novel, miRNA-eluting collagen-based scaffold with applications in regenerative medicine
A proprietary process developed at RCSI enables the production of reliable, shelf-stable, biocompatible scaffolds containing miRNA adjuncts with the ability to target numerous pathways such as chondrogenesis, osteogenesis and inflammation. miRaColl's versatility as a platform technology means that this product can be easily adapted, through tailoring the structural composition, vectors and the specific microRNA, for the repair of other soft and stiff tissues such as skin, nerve and bone. miRaColl also offers a platform for the localised delivery of RNA therapeutics.